Purpose
The objective of this study was to determine the relationship between sedentary time and total; cardiovascular disease (CVD); coronary heart disease (CHD); and cancer mortality in a prospective, multiethnic cohort of postmenopausal women.
Methods
The study population included 92,234 women aged 50–79 years at baseline (1993–1998) who participated in the Women’s Health Initiative Observational Study through September 2010. Self-reported sedentary time was assessed by questionnaire and examined in 4 categories (≤4, >4–8, ≥8–11, >11 hours).
Results
The mean follow-up period was 12 years. Compared with women who reported the least sedentary time, women reporting the highest sedentary time had increased risk of all-cause mortality in the multivariate model For all mortality outcomes, there were significant linear tests for trend.
Conclusions
There was a linear relationship between greater amounts of sedentary time and mortality risk after controlling for multiple potential confounders.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896923/
